https://www.ceesdekker.net - An Overview
https://www.ceesdekker.net - An Overview
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Human Rad51 filaments on double- and one-stranded DNA: correlating typical and irregular sorts with recombination perform.
[Laughs] ‘It was unquestionably an excellent threat! At enough time, I was very well mindful that it could go wrong and that I could turn out to be significantly less profitable, but I just ignored that. Curiosity has constantly been my strongest driving force. And by chance it all labored out.’
Our get the job done was speedily followed up by Other folks, most notably by Phaedon Avouris and colleagues at IBM, who in October 1998 posted their findings on transistors produced from one- and multi-walled carbon nanotubes in Utilized Physics Letters.
This yielded a breakthrough. In just just a few months, we were in the position to measure transportation by means of somebody solitary-walled carbon nanotube. Based on lower-temperature experiments by a brilliant PhD scholar in my group, Sander Tans (now a valued colleague and professor at Delft College of Technologies by having an active investigation lab at AMOLF in Amsterdam), we confirmed that carbon nanotubes have been legitimate quantum wires with quite long (micrometres) electronic coherence lengths — confirming theoretical predictions of metallic conduct.
Microbiology has only existed to get a century, given that we started to examine micro-organisms additional very seriously. I assumed nanobiology was an correct term, simply because all molecular biological related interactions take place in the nanoscale: a protein is several nanometres in dimension, DNA is 2 nm thick.’
Several connected developments followed, the place our group recognized unique transistor variants which include one-electron transistors at home temperature and intramolecular nanotube junctions that acted as rectifying diodes, and coupled various transistors into small evidence-of-principle Digital circuits.
Instance (one) of bending configurations in 3D simulations of DNA rods on nanopores. A portion of the membrane is demonstrated in grey, the rim with the pore is highlighted in crimson, in addition to a 3D rendering on the movement in the DNA rod is displayed.
What if, in lieu of working with standard major-down silicon electronics, transistors may very well be developed from The underside up making use of one natural molecules as the switching aspects? This idea, which grew to become The premise of nowadays’s field of molecular electronics, 1st emerged within the seventies.
Resolving the step size in condensin-pushed DNA loop extrusion identifies ATP binding given that the step-generating process
An integrated microfluidic System for quantifying drug permeation throughout biomimetic vesicle membranes
1999, 1st measurement of the wavefunction of solitary molecular orbitals of carbon nanotubes; and discovery of kink heterojunctions of carbon nanotubes which gave decisive evidence for the new Luttinger description of interacting electrons in nanotubes
Visualization of unstained DNA nanostructures with advanced in-target transmission electron microscopy tactics
The biophysicist from Delft – who continues to be The most cited researchers https://www.ceesdekker.net within the Netherlands For many years – requires his responsibility to contribute to the clarification and popularisation of his get the job done with the border of physics and biology extremely seriously and consistently appears inside the media; if not to talk about his do the job, then about the connection among science and his Christian faith.